OrNet: Spatiotemporal Analysis of Organelle Morphology

Walter Avila, a student from Emory University, worked in the lab of Dr. Shannon Quinn. Abstract Modeling changes in organelle morphology in response to infections is pivotal in studying pathogenic behaviors. Mitochondria are the most meaningful organelles to study because their structure changes dramatically in the presence of potentially fatal infections. Accurately modeling mitochondria could

Using SpatialDE to characterize spatiotemporal changes in mitochondrial morphology

Brittany Dorsey, a sophomore from Mercer University, worked with Dr. Shannon Quinn and Dr. Fred Quinn to test the use of a new method to detect changes in organelle morphology. Abstract:   Intracellular bacterial pathogens have the capacity to greatly alter target organelles’ morphology, which can easily be visualized through fluorescence microscopy, but is more difficult